Heart Beat: October 2017


Great Variations in Home Blood Pressure Readings Linked to Dementia Risk

Heart Beat

Sizable fluctuations in home blood pressure readings were tied to a greater risk of Alzheimer’s disease, independent of high systolic blood pressure, according to a study published in the journal Circulation. In the study, men and women ages 60 and older took their blood pressure readings at home every day for a month. Those who had the highest fluctuations had more than twice the risk of developing Alzheimer’s disease within five years as those with stable readings. The study did not show that treating someone with highly variable home blood pressure readings would lower the Alzheimer’s risk. However, the researchers did suggest that effectively managing high blood pressure and following other healthy behaviors, such as exercising regularly, getting sufficient sleep, and following a healthy diet, could be considered reasonable risk-lowering measures against the development of Alzheimer’s and other forms of dementia. There are, however, no proven ways to prevent the onset of Alzheimer’s disease. Determining whether fluctuating blood pressure is a modifiable risk factor for Alzheimer’s would have to be proved in a separate study. If you take your blood pressure at home and notice your readings vary greatly from one day to the next or within the same day, alert your doctor. The readings could be the result of improper technique or problems with the monitor itself. The readings may also be a sign of poorly controlled high blood pressure, which should be treated promptly with medications, diet, exercise, and other lifestyle changes.

Discontinuing Statins After First Ischemic Stroke May Raise Risk of Second Stroke

Quitting statins three to six months after an initial ischemic stroke significantly raises your risk of having a second stroke within a year. That’s according to a large study of people who had been hospitalized with a stroke. The research, published in the Journal of the American Heart Association, found that the risk of having a second stroke within a year rose by 42 percent. The risk of death from any cause was about 37 percent within that first year. There was no significant change in stroke survivors who stuck with their statin regimen. Statins are widely prescribed medications designed to reduce levels of LDL (“bad”) cholesterol. High cholesterol levels are associated with a higher risk of ischemic stroke—the type of stroke caused by a narrowing of or blockage in an artery supplying blood to the brain. It’s not uncommon for people who have reached their goal with cholesterol to simply stop taking their statins. But controlling high cholesterol is an ongoing process that may require statins or other LDL-lowering drugs for life. Researchers say that instead of quitting statins, a person may want to talk to his or her doctor about possibly lowering the dosage. This is true if you have some side effects from high doses. A change in dosage or a switch to a different statin may be enough to eliminate side effects.

Increased Risk of Blood Clots Found in Recently Diagnosed Cancer Patients

A recent study published in the Journal of the American College of Cardiology found that cancer patients face an increased risk of an arterial thromboembolism within the first six months after their diagnosis. An arterial thromboembolism is a blood clot or piece of plaque that has dislodged from one location and moved to another spot in an artery, causing a blockage of blood flow. In the study, researchers found that the greatest risk for an embolic event, such as a heart attack or stroke, was found in people with lung cancer. The study also found that the risk of a stroke or heart attack was twice as high in cancer patients as it was in similar people who did not have cancer. The increased risk seems to disappear by the end of the first year after diagnosis. Reasons for the increased blood clot risk aren’t well understood. Researchers suggested that one explanation may lie with the shared risk factors for cancer and clotting problems. Among the risk factors are smoking, obesity, and advanced age. Certain cancer treatments may also increase the risk of an embolism forming in an artery. If you have been diagnosed with any type of cancer, you should be monitored for blood clot formation. Researchers added that this study wasn’t enough evidence to suggest that cancer patients automatically be placed on statins or blood-thinning medications.


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