Stress and depression often go hand in hand, and for a woman with heart disease this combination is often an unavoidable reality. Its estimated that 15 to 20 percent of American women have depression, with women being twice as likely to be depressed than men. And when depression is added to cardiovascular disease, there is a stronger likelihood of a worse cardiovascular outcome. While it isnt exactly clear what happens in the brain when people become depressed, the link between heart diseases impact on anxiety and depression is evident. Depression is two times more common in patients after a heart attack compared to the general population, and its crucial to detect it.