We would advise you to follow a low-fat diet, get regular exercise and take a cholesterol-lowering statin. Its not a sexy solution, but it makes sense. If you eat less and burn more calories, you will lose weight, and your cholesterol will drop. Add a statin, and it will drop further. Your cholesterol goal will depend on whether you have been diagnosed with coronary artery disease or have had a coronary event (secondary prevention) or are simply hoping to prevent one (primary prevention). If you have had an event, your LDL ("bad cholesterol") is far too high.