Fred Izenson was out of options when he visited Cleveland Clinic in 2005. A major coronary artery was blocked, and the grafts used to bypass it and supply blood to a portion of his heart had failed. After having three bypass surgeries, he didnt want a fourth. So the Kettering, Ohio, man and his doctors-including Cleveland Clinic interventional cardiologist Samir Kapadia, MD-decided to implant drug-eluting stents to reopen his occluded (blocked) artery. The stents-wire-mesh cylinders coated with a drug polymer-prop open and restore blood flow through occluded blood vessels. Three years later, and after a groundswell of concern about the safety of the medicated stents, Izenson and his implants are functioning well. "To me, there was no other option. I was glad to find a less-invasive procedure," says the 74-year-old magistrate judge. "As far as Im concerned, the medicated stents are a life-saver. I think Im doing very well."