MedicationNutrition & ExercisePreventionRelated ConditionsRisks What Common Drugs May Interfere with Your Heart Medications? Over-the-counter cold and flu medicines can be especially challenging to manage if you take blood pressure medications or have an arrhythmia. estaff Published: November 17, 2015 0 Print Email Facebook Twitter NSAIDs, anticoagulates, decongestants and sodium-heavy drugs like acetaminophen all pose threats if you take heart medications. Know your risks and why they occur. To continue reading this article you must be a paid subscriber Subscribe Subscribe to Heart Advisor Get the next year of Heart Advisor for just $20. And access all of our online content - over 2,000 articles - free of charge. Subscribe today and save 38%. It's like getting 5 months FREE! Already Subscribed? Click Here to Sign In | Forgot your password?