Features April 2011 Issue

Combination Therapy Often Best Approach to Treat Hypertension

Research shows that starting with two medications leads to healthier outcomes in the effort to control high blood pressure.

Patients with high blood pressure respond better when given two anti-hypertensive medications at the start of their treatment, compared to single-drug therapy, according to a study published online January 12, 2011, in the Lancet. Study findings suggest that a combination of medications should be the first choice of physicians treating hypertensive patients. The findings of the Aliskiren and the Calcium-Channel Blocker Amlodipine Combination as an Initial Treatment Strategy for Hypertension (ACCELE­RATE) trial contradict the "start low and go slow" philosophy that has been employed often through the years.

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