Chances are that if you dont take a blood pressure-lowering drug now, you may need to in the future. And if not you, someone close to you may need an antihypertensive medication. About one out of three American adults has high blood pressure, according to the Centers for Disease Control and Prevention. Controlling hypertension usually involves a combination of one or more blood pressure-lowering drugs, weight management, diabetes control, a heart-healthy diet, no smoking and regular exercise. In addition, there are other factors that go into devising a personalized treatment plan.