Features January 2017 Issue

Injectable Cholesterol-Lowering Drug Continues to Show Promise

Mild plaque buildup (lower right) allows for healthy circulation. But as plaque grows in a coronary artery, blood flow can eventually stop, causing a heart attack.

Injectable Cholesterol-Lowering Drug Continues to Show Promise

PCSK9-inhibitors, combined with statins, can bring cholesterol levels down significantly and may help reverse the build-up of plaque in the arteries.

A Cleveland Clinic study found that a newer, injectable drug to fight cholesterol appears to reverse plaque buildup in the arteries within 18 months. In the study, patients were given injections of the PCSK9 inhibitor evolocumab (RepathaŽ), as well as standard daily doses of a statin.

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