Heart Beat: January 2020
Many patients with high blood pressure require multiple medications in different classes to bring their blood pressure down into an acceptable range. Normalizing blood pressure is necessary to reduce the risk of heart attack and stroke. A large study conducted in Spain and reported in the Oct. 22, 2019, European Heart Journal found that taking the entire daily dose of hypertension medications at bedtime was significantly more effective in this regard. Compared with patients who took the medications upon awakening, those who took them at bedtime gained better blood pressure control and had fewer fluctuations. Over a mean of 6.3 years, this translated into lower rates of heart attack, stroke, heart failure, revascularization and cardiovascular death.